• Online Features  This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on Web of Science (1)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

WILLIAM J. OLIVER, M.D.; WILLIAM R. COLLINS, M.D.

AMA J Dis Child. 1960;99(3):261-275.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In the course of conducting an investigation of a family group showing proteinuria and hypercholesteremia but without evidence of nephrosis or other disease,* data were obtained showing the presence of two concurrent but nevertheless independent hereditary traits: (a) proteinuria, with an associated abnormality of the serum protein fractions, and (b) hypercholesteremia, also associated with a distinct abnormality of the serum protein fractions. A review of the literature failed to reveal any previous reports of either the association of abnormal concentrations of serum protein fractions with familial proteinuria or the simultaneous occurrence in the same subjects of familial proteinuria and familial hypercholesteremia. The results of a study of two generations of a family group demonstrating these findings are reported.

Material and Methods

The patients comprising this study consisted of 16 persons of two generations of one family line.

Mode of Recognition and Chronological Sequence of Investigation

Seven of the subjects, all . . . [Full Text PDF of this Article]

Author Affiliations

University of Michigan Medical Center, Ann Arbor, Mich. (Dr. Oliver).

Footnotes

During subsequent observation, one of the subjects (I-2) suffered an episode of coronary occlusion.

CiteULike    Connotea    Delicious    Digg    Facebook    Reddit    Technorati    Twitter     What's this?