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A Review of the Experience at Duke Hospital in Infants and Children During a Twenty-Two-Year Period (1933-1954)

CAROLYN COKER HUNTLEY, M.D.

AMA J Dis Child. 1958;95(5):477-480.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The incidence of sepsis following splenectomy, particularly in infants, is a subject of current interest. King and Shumacher¹ in 1952 reported the occurrence of meningitis in four of five infants splenectomized under 6 months of age for congenital hemolytic anemia. Smith et al.² in 1956 reported severe infections after splenectomy in 14, or 28%, of 50 infants and children. Gruber et al.³ reported overwhelming bacteremia with death in a premature infant 14 days after splenectomy for thrombocytopenic pupura. Robinson⁴ reported pneumococcal meningitis in a 5-month-old infant six weeks after splenectomy for congenital hemolytic anemia. In a review of 107 splenectomies in infants and children Gofstein and Gellis⁵ found severe infections after operation in 4 patients. They eliminated from their series those patients whose primary disease was a factor in increased susceptibility to infection.

On the other hand, there have been many reports of successful splenectomies . . . [Full Text PDF of this Article]

Author Affiliations
Winston-Salem, N. C.

From the Department of Pediatrics, The Duke University School of Medicine, Durham, N. C.: Present address: The Bowman Gray School of Medicine, Winston-Salem, N. C.

Footnotes
Received for publication May 3, 1957.

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