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Effect of Supplementing Soybean Proteins with Lysine and Other Amino Acids
R. J. BLOCK, Ph.D.;
D. W. ANDERSON, Ph.D.;
H. W. HOWARD, Ph.D.;
C. D. BAUER, Ph.D.
AMA J Dis Child. 1956;92(2):126-130.
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Ever since the recognition of Osborne and Mendel,1 in the early years of the present century, of the dietary indispensability of certain amino acids, physicians, nutritionists, and others have looked forward to the practical possibility of improving the protein value of certain foods by direct supplementation with specific amino acids. This hope can now be partly satisfied because of the availability of L-lysine, DL-methionine and L-cystine in commercial quantities at a reasonable price. There is no doubt that the addition of lysine to wheat products results in a significant improvement in the nutritive value of the proteins.2 Likewise, small additions of cystine or methionine improve the protein value of milk, meat, soy, and other leguminous vegetables.2 However, care must be taken not to allow initial enthusiasm to exceed proved scientific evidence.
The formation of tissue proteins is an "all or none" proposition in the
. . . [Full Text PDF of this Article]
Author Affiliations
New York
From the Prescription Products Division, The Borden Company.
Footnotes
Accepted for publication March 19, 1956.
Present address of Dr. Block is Boyce-Thompson Institute, Yonkers 3, N. Y.
The fact that soy proteins are a little more deficient in methionine than milk is of no consequence in practical infant feeding, for, as Mendel pointed out many years ago, optimal growth and well being can be achieved by supplying a larger quantity of a nutritionally inferior protein than would be necessary with a protein of higher biological value, providing the inferior protein does not show any marked deficiency of an essential amino acid. In fact, calculation will show that Mull-Soy equivalent to 40 calories will supply more than the 90 mg. of lysine per kilogram per day needed by infants. Normally, 110 calories of Mull-Soy are fed per kilogram of body weight per day.
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