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An Electrophoretic Study of Urinary Proteins in the Nephrotic Syndrome and Acute Glomerulonephritis

WALTER HEYMANN, M.D.; CAROLINE GILKEY; MILDRED LEWIS

AMA J Dis Child. 1956;91(6):570-576.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Globulin was detected in protein-containing urine for the first time in 1866, by Lehman.¹ From then on, several studies * have dealt with a possible relationship of globinuria to the outcome of renal diseases. Discrepancies in the results and conclusions obtained may be due to the use of older, inaccurate methods and to the fact that single or few examinations were done in individual cases. Further confusion also derived from the poorly defined classification of cases used for investigation, usually grouped under the term of "Bright's disease." We will confine our communication to 11 children who suffered from acute postinfectious hemorrhagic glomerulonephritis and to 32 children suffering from the nephrotic syndrome. According to a recently proposed classification,¹⁰ children who had the nephrotic syndrome in its so-called "pure form" were not separated from children who at one time or another had the disease with hematuria, hyperten sion, or azotemia. According . . . [Full Text PDF of this Article]

Author Affiliations
Cleveland

From the Department of Pediatrics, Western Reserve University School of Medicine.; Dr. Louis Pillemer, Department of Pathology, and Dr. Carl H. Miller, Department of Biochemistry, Western Reserve University School of Medicine, gave assistance in this work.

Footnotes
Received for publication Nov. 8, 1955.

Supported by grants from the National Institutes of Health, U. S. Public Health Service (A-44), and the American Heart Association, Inc.

References 2-9.

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