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Report on a Child Without Fibrinogen and Review of the Literature

ROBERT W. PRICHARD, M.D.; ROBERT L. VANN, M.D.

AMA Am J Dis Child. 1954;88(6):703-710.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE COMPLETE congenital absence of fibrinogen is apparently one of the most unusual anomalies, since only 21 cases have been reported to date.* In this presentation the 22d patient is discussed and a brief review appended. Aside from their rarity, these patients present findings which throw light on other, commoner problems and are examples of conditions which are impossible to produce experimentally at present.

A 19-day-old white boy, the child of unmarried parents, was referred to the North Carolina Baptist Hospital on Feb. 1, 1952, for the diagnosis and treatment of persistent bleeding from the umbilical cord. He was the second child of a 35-year-old mother, the product of a full-term gestation, without complications, with spontaneous delivery after an eight-hour labor in another city. The mother had been given 5 mg. of a vitamin K analogue prior to delivery. On the second day of life, oozing of blood from the . . . [Full Text PDF of this Article]

Author Affiliations
WINSTON-SALEM, N. C.

From the Departments of Pathology and Pediatrics of the Bowman Gray School of Medicine of Wake Forest College.

Footnotes
References 1-17. Diamond, L. K., and Borges, W.: Congenital Afibrinogenemia, read before the International Society of Hematology, Buffalo, Aug. 23-26, 1948 (three cases reported). 703

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