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JAMES N. YAMAZAKI, M.D.; STANLEY W. WRIGHT, M.D.; PHYLLIS M. WRIGHT, M.D.

AMA Am J Dis Child. 1954;87(4):448-463.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

INVESTIGATION on animal fetuses and clinical studies of postconception pelvic irradiation have demonstrated a damaging effect of radiation upon the development of the fetus.* This paper presents a report of investigations being made on the effects of the atomic explosion on fetuses of women who were in Nagasaki on Aug. 9, 1945.

COLLECTION OF DATA

A. Patient Selection.—This study was conducted in Nagasaki during the first half of 1951. On the basis of information obtained from the pregnancy records of the genetics program, lists were made of all women who, at the time of the explosion, were of childbearing age (for the purposes of this study, 17 to 50 years of age) and were residing in Nagasaki. A home investigation was done by trained personnel to determine if the mother had been pregnant at the time of the bombing. Conception was considered to have occurred two weeks after the . . . [Full Text PDF of this Article]

Author Affiliations
LOS ANGELES

From the Laboratories of the Atomic Bomb Casualty Commission, Hiroshima, Japan, and the Department of Pediatrics, University of California Medical Center.

Footnotes
This work was sponsored by the Atomic Bomb Casualty Commission, National Academy of Sciences—National Research Council, with funds supplied by the United States Atomic Energy Commission.

Presented in part before the Society of Pediatric Research, Atlantic City, N. J., May, 1953. References 1-22.

Of the symptoms commonly encountered in the syndrome of radiation sickness, epilation, purpura and petechiae, and oropharyngeal lesions are generally considered to be the most reliable evidence of radiation injury and are designated in this study as "major" diagnostic signs. Malaise, vomiting, fever, and diarrhea, which are frequently manifestations of radiation sickness, may occur with many other illnesses. Considering the sanitary conditions which prevailed in the city immediately following the explosion, these latter symptoms are considered of "minor" importance in diagnosing radiation disease.

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