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  Vol. 66 No. 1, July 1943 TABLE OF CONTENTS
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VARIATION IN DIPHTHERIA ANTITOXIN TITERS OF HUMAN SERUM

REPORT OF AN EXTENDED STUDY, WITH SPECIAL REFERENCE TO AN ENDOCRINE AND VITAMIN RELATIONSHIP

MARY M. SCHMECKEBIER, M.D.

Am J Dis Child. 1943;66(1):25-36.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The literature records few determinations at frequent intervals of the diphtheria antitoxin titer of the blood serum of the same person over a period of several years. In 1925 Hamburger1 reported a study of 6 subjects on whose blood serum antitoxin determinations were done on several occasions. No more than five determinations were done on any 1 subject, and the longest interval between the initial and the final determination of the antitoxin titer was one and one-half years. In 1 subject there was an increase in the antitoxin titer from 0.01 to 0.75 unit per cubic centimeter within two and one-half months without any apparent stimulus. In the other subjects there was considerably less variation. In 1929 Fitzgerald2 published a paper on variations in the antitoxin content of serums of 6 adults over periods of from one to six years. In this article the amount of antitoxin in . . . [Full Text PDF of this Article]


Author Affiliations



SAN FRANCISCO

From the Children's Hospital and the George William Hooper Foundation for Medical Research of the University of California.


Footnotes



E. Charles Fleischner Endowment Fund Fellow.



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