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BRUCE CHOWN, M.D.

Am J Dis Child. 1939;57(3):489-505.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Giant cell pneumonia (Riesenzellenpneumonie, Hecht;¹bronchopneumonie à plasmodes, Masson and Paré²) is a rare pathologic condition occurring in children, usually between the ages of 6 months and 2 years. It most commonly follows measles but may occur as a sequel to other infectious diseases or in association with tuberculosis. There does not appear to be anything to distinguish it clinically from other long-drawn-out, diffuse pneumonias. Histologically, one finds a greater or lesser number of giant cells in alveoli; often they are extremely numerous (fig. 1 A). Careful examination shows that there is a peculiar transformation of the alveolar lining membrane, with thickening, hyalinization and coalescence of the lining cells (fig. 1 B and C). The lesions have been described in detail by Hecht,¹ and their development has been studied by Masson and Paré.² Karsner and Meyers,³ on reconstructing the giant cells, observed that what appeared . . . [Full Text PDF of this Article]

Author Affiliations

From the wards and St. Agnes Guild Laboratories of the Children's Hospital.

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