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III. SERIAL TITRATIONS ON TREATED AND UNTREATED PATIENTS WITH HAY FEVER

WILLIAM M. SCHMIDT, M.D.; VERNON W. LIPPARD, M.D.

Am J Dis Child. 1938;56(3):550-560.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Because of its relative frequency and clearly defined seasonal incidence, hay fever has been studied by immunologic methods more often than other allergic disorders which manifest sporadic symptoms. Nevertheless, there are available only limited and contradictory data concerning normal fluctuations and the effect of treatment on the passive transfer antibody titer.

A technic for titration of passive transfer antibody by neutralization, which we previously reported,¹ appeared to offer another and perhaps more exact method of approach.

The purpose of this investigation was to determine by serial titrations the fluctuations of passive transfer antibody titer in treated and untreated patients with hay fever. The relation of the titer to the amount of previous treatment and the intensity of clinical symptoms was also recorded.

METHOD AND SUBJECTS

Titration.—The method of titration was described in detail in a previous report.¹ It is briefly as follows: 1. A series of mixtures of . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the New York Hospital and the Department of Pediatrics, Cornell University Medical College.

Footnotes
Read in part at meetings of the Pediatric Section of the New York Academy of Medicine, Dec. 10, 1936, and the Society of Pediatric Research, May 3, 1937.

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