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  Vol. 55 No. 6, June 1938 TABLE OF CONTENTS
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MELORHEOSTOSIS LÉRI

JAMES B. GILLESPIE, M.D.; JOHN A. SIEGLING, M.D.

Am J Dis Child. 1938;55(6):1273-1279.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In 1922 Léri and Joanny1 first described a type of pathologic change of the bone for which they proposed the term melorheostosis, or flowing hyperostosis of a limb. The condition, which can be identified roentgenographically, is characterized by a dense cortical hyperostosis causing an enlargement of the affected part and extending in a linear streak along the bones of an extremity into some of the tarsal or carpal bones. In the cases reported, with one exception, the changes were confined to a single extremity, either upper or lower; this localization suggested to Putti2 the name osteosis eburnisans monomelica.

There is no unanimity of opinion as regards the etiology of the condition. Kraft3 summarized four theories: It has been ascribed to (1) a vasomotor neurosis in which the flow of blood to the affected part is altered, (2) an infectious process, (3) a constitutional endocrine disturbance and (4) . . . [Full Text PDF of this Article]


Author Affiliations

URBANA, ILL.

From the Department of Pediatrics and the Department of Orthopedics, Carle Hospital Clinic.



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