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I. R. JANKELSON, M.D.

Am J Dis Child. 1936;52(4):892-898.

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Judd¹ is universally given credit for first recognizing duodenitis as an operative and pathologic entity. The findings at operation were described by him as hyperemia and stippling of the serosa of the duodenal bulb. There is little infiltration; so the thickness of the duodenal wall appears normal or only slightly increased. When the duodenal cap is opened, the mucosa appears unbroken, is either diffusely or locally inflamed, bleeds easily on manipulation and on close inspection may present one or more small, superficial fissures or ulcerations. The microscopic changes were described in this country by MacCarty² and Wellbrock.³ They are characterized by a thickening of the mucosa and submucosa due to edema and congestion and by infiltration with polymorphonuclear leukocytes, lymphocytes, plasma cells and endothelial leukocytes. There are some cellular destruction and denudation. The epithelial cells may present various stages of degeneration. The serosa is usually only slightly . . . [Full Text PDF of this Article]

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BOSTON

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