This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

A BIOCHEMICAL INQUIRY INTO ITS PHYSIOLOGIC SIGNIFICANCE

HILDE BRUCH, M.D.; DONOVAN J. McCUNE, M.D.

Am J Dis Child. 1936;52(4):863-869.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The imposing size of the adrenal bodies in the human fetus and in the newly born infant has long attracted the attention of anatomists. The first detailed histologic description of the involutional process whereby these glands are converted into the mature but relatively smaller organs of childhood and adult life was published by Thomas¹ in 1911. In an investigation of the response of the adrenal glands during infections, Thomas called attention to the fact that these structures normally undergo extensive morphologic reorganization during the first year of life: The inner zone of the cortex (zona reticularis), which is relatively wide and conspicuously hyperemic at birth, suffers complete degeneration and is encroached on and replaced by the rapidly growing medullary portion of the gland. More exact information concerning the details of the maturation of the adrenal glands was contributed by the researches of Kern,² Kawamura,³ Landau,⁴ Lewis . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Diseases of Children, College of Physicians and Surgeons, Columbia University, the Sloane Hospital for Women, and the Babies Hospital.

Footnotes
Aided by a grant from the Emergency Committee in Aid of Displaced Foreign Physicians.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?