This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

ANNE TOPPER, M.D.; HAROLD ROSENBERG, M.D.

Am J Dis Child. 1936;52(2):266-279.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

There is known to be an increase in metabolism in all infections. As fever is nearly always present, it is difficult to say whether this increase is due to the fever or to other factors. It is known that fever produces a rise in basal metabolism—a rise which follows van't Hóff's law, which may be stated as follows: With an increase in temperature of 10 C. (18 F.), the velocity of chemical reactions increases between two and three times. DuBois¹ studied the metabolism in the various fevers and found that in 90 per cent of them the course closely followed this law. The increase in metabolism associated with fever is largely the result of the toxic destruction of protein which occurs more or less in all infections. The more toxic the condition, the greater the destruction of body protein, and the higher, therefore, the metabolism.

In febrile tuberculosis the . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Pediatric Service of Dr. Béla Schick, Sea View Hospital, Staten Island, N. Y.

Footnotes
A preliminary report of this work was made at a meeting of the Section of Pediatrics of the New York Academy of Medicine, New York. Jan. 10. 1935.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?