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PLACENTAL TRANSMISSION OF ANTIFIBRINOLYSIN AND ANTISTREPTOLYSIN

VERNON W. LIPPARD, M.D.; GEORGE W. WHEELER, M.D.

Am J Dis Child. 1936;52(1):61-66.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In previous investigations¹ it was observed that the antistreptolysin titer of infants at the onset of infections was lower than that of older persons and that their antistreptolysin response to infection with beta hemolytic streptococci was minimal. Furthermore, Wilson, Wheeler and Leask² observed that the average antistreptolysin titer of a group of new-born infants (56 units)³ was approximately that of their mothers (50 units). Repeated determinations showed that the mothers' titers remained at a constant level while those of the infants diminished progressively. Wilson and her associates considered this an indication of placental transmission of the antibody. Blood drawn from the umbilical cords of the majority of infants studied by Coburn and Pauli⁴ contained more antistreptolysin than did the corresponding maternal blood.

Lippard and Johnson¹ encountered occasional infants whose blood clots showed maximum resistance to dissolution by hemolytic streptococci during the early part of an . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the New York Hospital and Departments of Pediatrics and Applied Bacteriology, Cornell University Medical College.

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