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TREATMENT WITH CHOLESTEROL-FREE DIET IN TWO CASES

WARREN M. SPERRY, PH.D.; BÉLA SCHICK, M.D.

Am J Dis Child. 1936;51(6):1372-1384.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Rowland¹ defined essential xanthomatosis as "a heredofamilial, constitutional disorder of metabolism in which a deposition of fat-like mixtures, particularly cholesterol and its ester, takes place in the tissues and blood.... The pathologic change appears in the form of granuloma-like accumulations arising in various parts of the body." Since an accumulation of excessive amounts of cholesterol is a dominant feature of this disease, restriction of cholesterol in the diet is a rational therapeutic procedure, and it has been tried in a few instances, with considerable success. Herrmann and Nathan² observed definite clinical improvement in two patients after treatment with a low cholesterol diet (P flanzenkost), the description of which was not given. In one of them the cholesterol content of the blood serum decreased from 580 to 300 mg. per hundred cubic centimeters during four months on the diet; in the other the amount of serum cholesterol remained within . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Chemical Laboratory, Babies Hospital, and the Pediatric Service, Mount Sinai Hospital.

Footnotes
This investigation was assisted by a grant from the Josiah Macy Jr. Foundation.

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