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LEWIS K. SWEET, M.D.; H. J. K'ANG

Am J Dis Child. 1935;50(3):699-734.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The fat-soluble factor, vitamin A, although not yet isolated in pure form and although totally unknown until the last decades, has held the attention of clinicians, through the manifestations of its deficiency, since the earliest times. Night blindness, one of the first symptoms of avitaminosis A, was known to Hippocrates, and the beneficial results of a liver diet in the treatment of this disorder were described by Paul of Aegina.¹ The more advanced symptom complex, keratomalacia, was not described until the middle of the last century, however, Brown² in 1827 and Fischer³ in 1846 being credited with having given the first descriptions. Arlt⁴ in 1851 also described the condition, and in 1862 Bitot⁵ linked hemeralopia with xerosis of the conjunctivae. Complete descriptions of the disease were first given by da Gama Lobo⁶ in 1864 and by von Graefe⁷ in 1866. The relationship of . . . [Full Text PDF of this Article]

Author Affiliations
PEIPING, CHINA

From the Department of Medicine and Pathology, Peiping Union Medical College.

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