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II. CALCIUM IN THE BLOOD IN RICKETS

EDWARD L. COMPERE, M.D.; FRANKLIN C. McLean, M.D., PH.D.; A. BAIRD HASTINGS, PH.D.

Am J Dis Child. 1935;50(1):77-83.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The literature and the theoretical considerations concerning the rôle of calcium in the formation of bone, and more particularly in rickets, have recently been reviewed by Peters and Van Slyke.¹ An extensive review is therefore unnecessary here. Since the work of Howland and Marriott,² it has been generally agreed that while the total calcium content of the serum is occasionally low in rickets such a reduction is not a consistent or a necessary factor in the pathologic physiology of this disease.

Benjamin and Hess³ recently studied the state of calcium in normal and rachitic serums, using a combination of the methods of adsorption and ultrafiltration. They concluded that of the diffusible calcium from normal serum about two thirds is in the form of an adsorbable calciumphosphorus complex. In rickets they found a diminution in the adsorbable fractions of calcium and an increase in the fractions designated by . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Division of Orthopedic Surgery, Department of Surgery, the Physiological Laboratory and the Lasker Foundation for Medical Research, the University of Chicago.

Footnotes
This work was aided by grants from the Quaker Oats Company and the Josiah Macy Jr. Foundation.

A preliminary communication was published in the Proceedings of the American Society for Clinical Investigation (J. Clin. Investigation 13:687, 1934).

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