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WITH A DESCRIPTION OF A NEW PATHOGENIC ANAEROBE, BACILLUS DIFFICILIS

IVAN C. HALL, PH.D.; ELIZABETH O'TOOLE

Am J Dis Child. 1935;49(2):390-402.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Following our first article on the bacterial flora of first passage specimens of meconium from fifty new-born infants¹ we studied the daily microbial changes in the feces of ten normal breast-fed infants up to the tenth day, when they left the hospital.

HISTORICAL REVIEW

The early invasion of the intestinal tracts of new-born infants by bacteria, either ascending or descending, often within ten hours after birth and before feeding, first observed microscopically by Breslau² in 1866, was confirmed by Billroth³ in 1874 and by Nothnagel⁴ in 1881. Using iodine as a stain, Nothnagel assumed to identify Saccharomyces ellipsoideus, Bacillus subtilis and the so-called clostridium of Prazmowski, which he regarded as identical with Bacillus amylobacter of Trecul and van Tieghem and the "vibrion septique" of Pasteur; but we feel that even now, with greatly improved methods of staining, identification of any of these is impossible.

Nothnagel was . . . [Full Text PDF of this Article]

Author Affiliations
DENVER

From the Department of Bacteriology and Public Health, University of Colorado School of Medicine and Hospitals.

Footnotes
This investigation was supported in part by grants from the Commonwealth Fund of New York and the Child Research Council of Denver.

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