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JOHN J. SLAVENS, M.D.

Am J Dis Child. 1934;47(4):821-835.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Multiple myeloma may be defined as a primary malignant tumor of bone marrow characterized by multiple foci in long and flat bones of the skeleton and usually associated with anemia, Bence-Jones proteinuria, rare metastasis and a fatal termination. Maclntyre¹ described the condition in 1850, but von Rustizky² first recognized it as a specific disease of the bone marrow, and referred to it as myeloma. Kahler,³ in 1889, called attention to the associated proteinuria, hence the reference in the literature to "Kahler's disease." Geschickter and Copeland,⁴ in 1927, reviewed 425 cases from the literature, and stated that multiple myeloma was present in only 0.03 per cent of all malignant conditions. Symmers⁵ found only three cases of the condition in the course of 6,000 postmortem examinations performed at Bellevue Hospital, New York City. Thus the rarity of multiple myeloma is evident.

The disease usually afflicts persons well . . . [Full Text PDF of this Article]

Author Affiliations
Fellow in Pediatrics, the Mayo Foundation ROCHESTER, MINN.

Footnotes
Read before the Northwestern Pediatric Society, Rochester, Minn., on Nov. 4, 1932.

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