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  Vol. 46 No. 6, December 1933 TABLE OF CONTENTS
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APLASIA AXIALIS EXTRACORTICALIS CONGENITA

(MERZBACHER-PELIZAEUS DISEASE)

ORMAN C. PERKINS, M.D.

Am J Dis Child. 1933;46(6):1343-1355.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In the cases to be reported I was confronted with a peculiar situation. Four children of the same parents had a disease at about the same age; the characteristics of the disorder in each case were similar throughout the course of the illness. No evidence of a similar condition was found in the family history as far back as the third generation. The father of the children had a four plus Wassermann reaction; one patient had a four plus and one a one plus Wassermann reaction. The first question that arises is, "Has the condition a hereditary basis?"

"Hereditary" is the term applied to a biologic process by which the characters of body and mind are transmitted from parent to offspring. If such a process in the nature of a disease is passed on from generation to generation, the disease is spoken of as a familial disease, in other words, . . . [Full Text PDF of this Article]


Author Affiliations

Professor of Neurology, Long Island College of Medicine BROOKLYN

From the Neurological Service, Kings County Hospital.



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