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JAUNDICE OF THE NUCLEAR MASSES OF THE BRAIN

H. M. ZIMMERMAN, M.D.; HERMAN YANNET, M.D.

Am J Dis Child. 1933;45(4):740-759.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

An opportunity presented itself in the last five years to study both clinically and by postmortem examination two cases of kernikterus. We have also had the privilege of studying the histories and subsequent courses of two children in whom extensive dysfunction of the central nervous system developed following severe neonatal jaundice. It is the purpose of this paper to record these four cases in detail and to review the available literature on the subject.

Kernikterus is a term coined by Schmorl¹ in 1903 to designate jaundice of various nuclear masses of the brain, but it was Orth² who, in 1875, first described this condition. The structures most commonly affected are the caudate, lenticulate, subthalamic and dentate nuclei, the thalami, the mammillary bodies, the cornua ammonis, the nuclei of the cranial nerves, the olives and even parts of the cerebellar cortex, as well as the anterior and posterior horns . . . [Full Text PDF of this Article]

Author Affiliations
NEW HAVEN, CONN.

From the departments of Pathology and Pediatrics, Yale University School of Medicine, and the Pathological and Pediatric Services of the New Haven Hospital and Dispensary.

Footnotes
Read in part before the American Association of Pathologists and Bacteriologists, Philadelphia, April 29, 1932.

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