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ASSOCIATED WITH FUNDAMENTAL DISTURBANCES OF BONE AND PIGMENT METABOLISM (COOLEY-VON JAKSCH)

G. H. WHIPPLE, M.D.; W. L. BRADFORD, M.D.

Am J Dis Child. 1932;44(2):336-365.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The statement that knowledge relating to this disease condition is in an unsatisfactory state will be accepted without argument. Many authors feel that von Jaksch did not describe this disease, and that the term "von Jaksch's anemia" includes a miscellaneous group of diseases. As described by Cooley¹ this disease now has a well established and cleancut clinical picture, with careful reports from a number of clinics in this country. Cooley² considered the condition as essentially due to hemolysis, and related the bone changes to the extreme hyperplasia of the red marrow. Wollstein and Kreidel³ referred to the disease as a familial hemolytic anemia. It is fair to state that the study of anatomic material has not been as complete and satisfactory as the clinical reports. For this reason it seemed wise to report in detail the gross and histologic observations in the two cases herein reported.

Pigmentary . . . [Full Text PDF of this Article]

Author Affiliations
ROCHESTER, N. Y.

From the Departments of Pathology and Pediatrics, University of Rochester School of Medicine and Dentistry.

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