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REPORT OF A CASE WITH HISTOLOGIC OBSERVATIONS

C. R. TUTHILL, M.D.; M. G. LEVY, M.D.

Am J Dis Child. 1931;41(3):591-602.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In 1900, Oppenheim¹ described a disease of infants and young children that is characterized by weakness, hypotonia and loss of reflexes, without disturbances of mentality or of sensation. He believed that the disease was due to a delayed development of the lower motor neuron and of the voluntary muscles, because the disease often ended in recovery. While amyotonia congenita is a comparatively rare disease, in 1917 Faber² collected 115 cases, with 27 anatomic reports. This group does not include cases which from their description appear to be cases of amyotonia congenita, but which have been classified as the type of muscular atrophy described by Werdnig³ and Hoffman.⁴ According to Greenfield and Stern,⁵ and Grinker,⁶ there is no clinical differentiation possible in these two diseases. The Werdnig-Hoffman type of muscular atrophy has been considered familial as opposed to Oppenheim's disease, but familial cases of Oppenheim's . . . [Full Text PDF of this Article]

Author Affiliations
BUFFALO

From the Children's Hospital and the Laboratories of the Buffalo General Hospital.

Footnotes
Submitted for publication, Sept. 9, 1930.

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