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HEYWORTH N. SANFORD, M.D.; MARIAN M. CRANE, M.D.; ELEANOR I. LESLIE, M.D.

Am J Dis Child. 1930;40(5):1039-1044.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Red blood cells are hemolyzed by various agents, such as saponin,¹ cobra venom² and mushroom toxins,³ both in vivo and in vitro. The blood serum has the power of protecting the red cells against greater concentrations of these agents than the cells can withstand alone. Bile salts have the property of hemolyzing red blood cells, and the red cells are protected against such hemolysis by their blood serum.⁴ Of all the various hemolytic agents, the bile salts are the most interesting from a clinical point of view because of the question as to whether or not bile salts existing in the blood stream as the result of hepatic obstruction may cause hemolysis. Ponder has contributed an immense amount of painstaking work on this phenomenon.

Donnelly and Mitchell⁵ found that the degree of the hemolyzing power of bile salts for normal red blood cells, as well . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Department of Pediatrics, Rush Medical College, of the University of Chicago, and from the Presbyterian Hospital.

Footnotes
Submitted for publication, June 7, 1930.

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