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LEIF SALOMONSEN, M.D.

Am J Dis Child. 1930;40(4):718-724.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Clinical experience has fully established the antiketogenic effect of insulin in cases of diabetic ketosis, but the action of insulin in ketosis of nondiabetic origin is more uncertain. In adults living on a ketogenic diet, Herzberg¹ and Thannhauser and Mezger² found a decrease in ketosis after the administration of insulin. On the other hand, Burn and Ling³ found an increase in ketonuria in fasting rats after the administration of insulin. In normal rabbits, Collip⁴ has demonstrated that insulin can give rise to ketonuria, when the blood sugar falls as low as 0.065 and 0.045. Mainzer⁵ has seen that insulin shock in diabetic patients may be accompanied by an increased excretion of ketone bodies. According to investigations made by Freise and his co-workers in children with alimentary and diabetic ketosis,⁶ the antiketogenic action of the insulin arises only when the organism has a certain surplus . . . [Full Text PDF of this Article]

Author Affiliations
OSLO, NORWAY

From the Municipal Hospital, Department VIII.

Footnotes
Submitted for publication, March 28, 1930.

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