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COMPARISON BY SUPRAVITAL AND FIXED SMEAR METHODS

CARL H. SMITH, M.D.

Am J Dis Child. 1930;40(3):505-514.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Discrepancies in the differential count of the white corpuscles are at once evident when counts made from the supravital preparations are compared with those made from fixed smears. The difference usually rests in the lower polymorphonuclear neutrophil and higher lymphocyte percentage of the fixed smear. The predominance of lymphocytes in the differential white blood count has always been regarded as characteristic of the blood of the normal infant following the first two weeks of life. This evidence has in general been based on the results of counts made from the fixed smear. At times, a routine fixed smear reveals a lymphocyte count out of all proportion to the clinical picture, and a presumptive diagnosis of a blood dyscrasia is entertained.

As the supravital technic provides a means of studying living blood cells with a minimum of trauma, differential white counts obtained by this method are more accurate than those utilizing . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Pediatrics, Cornell University Medical College, and the New York Nursery and Child's Hospital.

Footnotes
Submitted for publication, Jan. 15, 1930.

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