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THE RESPIRATORY METABOLISM IN INFANCY AND IN CHILDHOODXI. THE RESPIRATORY EXCHANGE IN MARASMUS: EFFECT OF MUSCULAR ACTIVITY
JAMES R. WILSON, M.D.;
SAMUEL Z. LEVINE, M.D.;
MARGARET KELLY, R.N.
Am J Dis Child. 1930;39(4):736-746.
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A few workers1 have assigned the major rôle in the pathogenesis of infantile marasmus to an abnormal energy metabolism. Studies reported in the three preceding papers of the present series2 do not support this view. These studies demonstrated that the basal metabolism, the energy metabolism following the ingestion of the principal foodstuffs, protein, carbohydrate and fat, and the intermediary metabolism of the latter food factors were all essentially normal even in severe grades of infantile marasmus. The remaining derangement of energy metabolism, which may be a contributing factor in maintaining the marasmic state, is an abnormally elevated metabolic response to muscular activity. This phase of the subject will be considered in the present communication.
It must be emphasized at the outset that the evaluation of the muscular efficiency of infants is at best a rough approximation, since accurate methods for quantitatively estimating mechanical work in these subjects are
. . . [Full Text PDF of this Article]
Author Affiliations
SYRACUSE, N. Y.; NEW YORK
From the Department of Pediatrics, Cornell University Medical College, and the New York Nursery and Child's Hospital.
Footnotes
Submitted for publication, Nov. 14, 1929.
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