This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

ITS PROGNOSTIC VALUE IN CHILDREN WITH HEART DISEASE

M. H. EDELMAN, M.D.; L. HALPERN, M.A.; J. A. KILLIAN, PH.D.

Am J Dis Child. 1930;39(4):711-728.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since the discovery of urobilin, in 1868, by Jaffe, urobilinuria has been observed in a wide variety of clinical conditions. Although numerous hypotheses have been proposed to explain the origin of urobilin in both the normal and the diseased organism, information of positive value was unavailable until within the last few years. Peyton Rous and his collaborators have approached anew the entire problem of the physiology and pathology of urobilin. Their work includes the elaboration of a quantitative method for determining urobilinuria, described by Elman and McMaster.¹ This method possesses the two essential requisites for a clinical laboratory procedure, simplicity and accuracy, and it was adopted for the studies reported herein.

In a series of articles, Elman and McMaster presented abundant evidence to support the view that in the uninfected animal the intestinal tract is the only site of origin of urobilin. Urobilinuria is an expression of the inability . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Pediatrics and the Department of the Laboratories, New York Post-Graduate Medical School and Hospital.

Footnotes
Submitted for publication, Nov. 9, 1929.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?