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II. THE EFFECTS OF DIGITALIS ON THE SINUS RATE OF CHILDREN WITH RHEUMATIC FEVER AND CHRONIC VALVULAR HEART DISEASE

SIDNEY P. SCHWARTZ, M.D.; JOHN B. SCHWEDEL, M.D.

Am J Dis Child. 1930;39(2):298-315.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The purpose of this study was to determine the effects of digitalis on the sinus rate of children with rheumatic heart disease and signs of heart failure and to point out the relationship between the slowing of the sinus rate when present and the relief from symptoms. Attempts were made to determine whether the amounts of digitalis required to slow the sinus rate could be used as an index of its therapeutic dose for children with heart disease. Although a reduction of the sinus rate is no longer regarded as a therapeutic index for digitalis therapy in adults,¹ for children the drug is still used with this purpose in view.² Indeed, in recent years, such reduction in the sinus rate when accompanied by nausea and vomiting has been considered the criterion for determining the therapeutic dose of the drug for children with heart disease.³

Sutherland² reported . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Medical Service of Dr. B. S. Oppenheimer, the Montefiore Hospital for Chronic Diseases, New York.

Footnotes
Submitted for publication, October 26, 1929.

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