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ALFRED E. FISCHER, M.D.

Am J Dis Child. 1929;38(4):715-720.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

During a routine physical examination of a diabetic child, an obvious loss of subcutaneous tissue from the upper and middle portions of both arms was noted (fig. 1). This loss of tissue occurred at the site at which insulin had been injected. A photograph of this child taken a year previously showed that some atrophy, while not marked, had nevertheless been present at that time. A search of the literature revealed that a number of authors had recently described the same condition. Depisch¹ and Barborka² were the earliest to note the disappearance of fat from the subcutaneous tissue in diabetic patients as the result of the injection of insulin. Both of Barborka's cases occurred in women, while of Depisch's five cases, four occurred in women and one in a man. Shortly thereafter, Davison³ and Mentzer and Du Bray⁴ each reported a case in a woman. The . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Pediatrics, Mount Sinai Hospital.

Footnotes
Submitted for publication, May 7, 1929.

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