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JOHN McKENNEY MITCHELL, M.D.

Am J Dis Child. 1929;37(5):1008-1015.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The relative frequency with which iso-agglutinins and agglutinogens are found in the blood of the infant at birth and during the early days of life has been investigated frequently. Happ¹ found the blood group completely established at birth in 16.3 per cent of forty-nine cases, and McQuarrie² in 11 per cent of 180 cases. Other authors reported percentages varying from these to 78.7 per cent of 197 cases, the figure quoted by Jones.³

All investigators, with the exception of von Decastello and Sturli,⁴ agreed that the agglutinogens appear earlier and occur in a larger proportion of cases than the iso-agglutinins. A change has never been demonstrated in a blood group which was completely established. Happ 1 and Unger,⁵ however, pointed out apparent changes in group by the accession of iso-antibodies previously lacking, and Smith⁶ reported two cases in which the apparent change was caused . . . [Full Text PDF of this Article]

Author Affiliations
BRYN MAWR, PA.

From the Department of Pediatrics and the William Pepper Laboratory, School of Medicine, University of Pennsylvania.

Footnotes
Submitted for publication, Oct. 20, 1928.

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