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VIII. A COMPARATIVE STUDY OF THE DIRECT AND INDIRECT (LOCAL PASSIVE TRANSFER) METHODS OF SKIN TESTING WITH THE SCRATCH AND INTRADERMAL TECHNICS

M. MURRAY PESHKIN, M.D.; A. H. FINEMAN, M.D.

Am J Dis Child. 1929;37(1):39-50.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In the past decade, skin testing (scratch and intradermal) with various substances has come to play an important rôle in the determination of etiologic factors of bronchial asthma and allied conditions. The information derived from testing the patient himself, known as the "direct method" of skin testing, has brought about a rational method of treatment for allergic conditions. However, the testing of infants with asthma, and especially those with dermatoses such as eczema and urticaria, presents many difficulties. Prausnitz and Küstner¹ first demonstrated that when blood serum of a patient sensitive to a protein is injected intradermally into the skin of a normal person, the area in which the injection is made becomes locally sensitized to the specific protein. Local passive transfer of hypersensitiveness into normal human beings was verified by de Besche,² Coca and Grove³ and others. The specific reacting substance in the blood of a . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Children's Asthma Clinic, Mount Sinai Hospital.

Footnotes
Received for publication, Aug. 3, 1928.

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