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USE OF A SPECIFIC STREPTOCOCCUS ANTISERUM

SAMUEL J. LEVIN, M.B. (TOR.); JOHN P. PARSONS, M.D.

Am J Dis Child. 1925;30(2):232-237.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

REVIEW OF THE LITERATURE

The blanching test in scarlet fever was first described in 1918. Schultz and Charlton¹ found that by injecting 1 c.c. of normal or convalescent serum intradermally into a scarlet fever patient with a fully developed eruption, the rash could be made to disappear locally. They found that this area of blanching appeared in from five to six hours; was from 1 to 2 inches (2 to 5 cm.) in diameter and persisted as long as the rash lasted. They also found that the injection of serum from a patient acutely ill with scarlet fever did not have the capacity of blanching the rash.

This observation has been confirmed by numerous observers² since. These investigators, however, have reported a certain number of failures. Schultz and Charlton concluded that the serum of a scarlet fever convalescent patient "recovers its lost power of blanching the rash between . . . [Full Text PDF of this Article]

Author Affiliations
ANN ARBOR, MICH.

From the Department of Pediatrics and Infectious Diseases, University Hospital, University of Michigan.

Footnotes
Received for publication, May 22, 1925.

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