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WILLIAM T. FREEMAN, M.D.; LEWIS D. HOPPE, M.D.

Am J Dis Child. 1924;28(3):310-321.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Several years ago a new drug was introduced by Young, White and Swartz¹ for use as a germicide in the genito-urinary tract. Since its introduction this drug, mercurochrome-220 soluble, has found wide fields for employment, both in medicine and in surgery.

Mercurochrome is the sodium salt of dibromoxymercury-fluorescein, made by combining one atom of mercury with one molecule of dibromfluorescein and contains about 26 per cent, mercury. It has been shown that in dilutions of 1: 5,000 it kills Staphylococcus aureus in five minutes and B. coli in fifteen minutes. When given intravenously in doses of 0.005 gm. per kilogram of body weight, the resulting dilution with the blood is approximately 1: 13,000. Dissolved in defibrinated blood in strengths of 1: 8,000 the Streptococcus hemolyticus is killed in forty minutes, and when the dilution is made 1: 16,000 (well above that occurring with ordinary doses used intravenously) it kills . . . [Full Text PDF of this Article]

Author Affiliations
ATLANTA, GA.

From the Department of Diseases of Children, Emory University.

Footnotes
Received for publication, June 5, 1924.

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