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Pathological Case of the Month
Jeffrey M. Scricca, MD;
Joseph C. Alper, MD
Arch Pediatr Adolesc Med. 1997;151(6):627-628.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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AT AGE 10 years, a girl was referred to our dermatology service with a 4-month history of painful, nonhealing, oral erosions; hoarseness; and weight loss. She was unresponsive to treatment. Blisters subsequently developed on her trunk, neck, and face. To this point, her working diagnosis had been aphthous stomatitis and bullous impetigo, for which she had been treated with topical anesthetic and oral antibiotics.
On physical examination, the gingiva revealed beefy, red, superficial erosions (Figure 1). The labia majora had one 0.5-cm superficial erosion. The trunk, neck (Figure 2), and face had a few scattered, flaccid, clear fluid—filled bullae with a slightly erythematous base. A punch biopsy specimen was obtained from the midback (Figure 3).
Diagnosis and Discussion
Pemphigus Vulgaris
While pemphigus vulgaris is the most common form of pemphigus in adults, it is rare in children. A review of the literature reveals only 42 cases since its first description
. . . [Full Text PDF of this Article]
Author Affiliations
From the Department of Dermatology, Roger Williams Medical Center (Dr Scricca), and the Harvard Community Health Plan of New England (Dr Alper), Providence, RI.
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