
Maternal Hypertension in Very-Low-Birth-Weight Infants
Ernest Friedman, MD
1831 Forest Hills Blvd Cleveland, OH 44112
Arch Pediatr Adolesc Med. 1997;151(4):429.
 |
 |
| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
|
 |
 |
Kim et al1 find that infants born to mothers with mild maternal hypertension had fewer pulmonary complications than control infants or infants born to mothers with severe maternal hypertension. Neurobiologic features are suggested by reports linking the induction of breathing with dopamine lateralized to the right hemisphere and subclinical impairment of lung airways caused by airway smooth-muscle tone dysregulation by dopamine abnormalities induced by hypoxia.2,3 This hypothesis is supported by prenatal stress that reduces dopamine turnover in the right nucleus accumbens leading to depression in adult offspring4 and by optimal response organization at intermediate dopamine tone in a mediofrontostriatal activation system.5
These findings prompt a follow-up to assess whether these more optimal neonatal findings in infants born to mothers with mild maternal hypertension will be reflected in their long-term outcomes1 by monitoring behavioral correlates of asymmetrical brain functions, reflecting properties of neuronal activity and firing.
. . . [Full Text PDF of this Article]
CiteULike Connotea Del.icio.us Digg Reddit Technorati Twitter
What's this?
|