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Ernest H. Friedman, MD
Departments of Medicine and Psychiatry Case Western Reserve University 1831 Forest Hills Blvd Cleveland, OH 44112

Arch Pediatr Adolesc Med. 1996;150(3):329.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In their recent article, Dahl et al¹ state that 24 female subjects with atopic dermatitis had more difficulty falling asleep (P=.02) than did 35 male subjects with the same skin inflammation. The neurobiologic manifestations are suggested by reports linking immune function and wakefulness to dopamine lateralized to the right hemisphere, in which the metabolic rate is higher in females.² The fact that delay-dependent speeding of reaction time, indicating motor readiness, is abolished by depletion of dopamine subserving mood prompts neurochemical and pharmacotherapeutic investigation^3,4 of disruption of family activities because of aggressive behavior¹ by monitoring speech hesitation and switching pauses, reflecting properties of neuronal activity and firing.³ This method is supported by anger attacks reflecting central hyposerotonergic function,⁵ serotonergic-mediated inhibition of dopamine, optimal response organization at intermediate dopamine tone in a medial-frontal-striatal activation system,² and deactivation of the right hemisphere, a state marker . . . [Full Text PDF of this Article]

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