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  Vol. 149 No. 3, March 1995 TABLE OF CONTENTS
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Lead Mobilization Test in Children With Lead Poisoning: Validation of a 5-Hour Edetate Calcium Disodium Provocation Test

J. L. Iniguez, MD; G. Leverger, MD; C. Dollfus, MD; F. Gouraud, MD
Department of Pediatric Onco-Hematology Armand Trousseau Children's Hospital 26 Ave du Docteur Arnold Nelter 75571 Paris, Cedex 12, France

R. Gamier, MD; P. Beauvais, MD
Paris

Arch Pediatr Adolesc Med. 1995;149(3):338-340.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since 1985, more than 400 new cases of childhood lead poisoning were diagnosed in Paris, France. The resurgence of lead poisoning is a major public health concern.1,2 The treatment of these children with increased blood lead levels was consistent with the guidelines of the Centers for Disease Control and Prevention (CDC), Atlanta, Ga,2-4 which recommend a lead mobilization test for patients with intermediate lead intoxication to determine which children would benefit from chelation therapy.

However, performing 24-hour provocative tests in young children has proved difficult: urine collection is often incomplete, and hospitalization is often necessary. The aim of our study was to decrease the urinary collection period of provocative tests to 5 hours and to assess the validity of this shortened procedure.

Patients and Methods. During a 17-month period between May 1989 and October 1990, 34 edetate calcium disodium (CaNa2 EDTA) mobilization tests were attempted in 32 . . . [Full Text PDF of this Article]



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