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Terrance D. Wardinsky, MD; Ramon G. Montes, MD; Richard L. Friederich, MD; Robert B. Broadhurst, MD
Department of Pediatrics David Grant Medical Center 101 Bodin Circle Travis AFB, CA 94535-1800

Vicki Sinnhuber, PNP
Fort Ord, Calif

Dennis Bartholomew, MD
Biloxi, Miss

Arch Pediatr Adolesc Med. 1995;149(11):1281-1284.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Vitamin B₁₂ (cobalamin) deficiency is uncommon in infancy. It may be associated with (1) inadequate dietary intake (eg, breast-fed infants of strict vegetarian [vegan] mothers); (2) congenital defects in intestinal absorption and transportation (eg, absence or malfunction of gastric intrinsic factor, selective ileal transport defect, or transcobalamin II deficiency); or (3) defects in intracellular processing.^1,2 The main clinical feature of vitamin B₁₂ deficiency is megaloblastic anemia. We herein describe a female infant who presented with developmental delay at 12 months. She was recognized to have macrocytic anemia and methylmalonicaciduria associated with vitamin B₁₂ deficiency. Her anemia and developmental status improved after parenteral administration of cyanocobalamin. It appears that this deficiency developed after she was exclusively breast-fed by a mother with inadequate breast-milk vitamin B₁₂ levels secondary to gastric bypass surgery and a semivegetarian diet.

Report of a Patient.

A 12-month-old female infant was referred for . . . [Full Text PDF of this Article]

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