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Maria Lourdes Cruz, MD
Department of Pediatrics Division of Neonatology Perinatal Research Institute

Samiran Bhadra, MD; M. T. Ravi Subbiah, PhD
Department of Internal Medicine

Reginald C. Tsang, MBBS
Department of Pediatrics Division of Neonatology Perinatal Research Institute University of Cincinnati 231 Bethesda Ave Cincinnati, OH 45267-0541.

Arch Pediatr Adolesc Med. 1994;148(11):1212-1215.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A test for serum lipid peroxidation potential has been recently described.¹ Serum lipid peroxidation potential is an estimate of the susceptibility of serum lipids to oxidation. It is affected by the balance of circulating prooxidant (such as iron, copper, and high polyunsaturated-to-saturated fatty acid ratios) and antioxidant (such as vitamins E and C, ceruloplasmin, and selenium) factors.¹ The balance of these peroxidation factors may, in turn, be affected by health status^1,2 and diet.³

Little is known about the peroxidation of serum lipids in healthy, growing infants. Two studies^4,5 reported diminished antioxidant activity in cord blood vs adult blood. A study of erythrocyte susceptibility to oxidation, measured as erythrocyte tendency toward hemolysis when lipids in cell membranes are subjected to deliberate oxidation, has shown that erythrocytes of formula-fed infants hemolyze more readily than do erythrocytes of human-milk-fed infants.⁶

To our knowledge, there are no studies . . . [Full Text PDF of this Article]

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