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BEN Z. KATZ, MD; JAMES G. MCNAMARA, MD
Yale University School of Medicine Department of Pediatrics 333 Cedar St New Haven, CT 06510-8064

Am J Dis Child. 1991;145(12):1348-1349.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Sir.—We read with interest the article by Blanche et al¹ on infants with perinatally acquired human immunodeficiency virus (HIV) infection. We too have noted a bimodal pattern of HIV-related disease in our pediatric patients with acquired immunodeficiency syndrome (AIDS).² In the last few years we have become aware of a third pattern of HIV infection in children, namely, severe manifestations of disease early in life that lessen over the next 5 to 10 years without antiretroviral therapy. This pattern is illustrated in the following patient reports of three HIV-infected children born to drug-abusing mothers.

Patient Reports.—PATIENT 1.—A 10-year-old black twin boy was born be tween 34 and 36 weeks' gestation. He weighed 1520 g at birth. His Apgar scores were 8/9 at 1 and 5 minutes. The boy had an uncomplicated neonatal course and was discharged after 2 weeks weighing 1950 g. Within his first 10 . . . [Full Text PDF of this Article]

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