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MARIA ASSUNTA PESARESI; STEFANO MICELI SOPO, MD; MARIA PASTORE, MD; ACHILLE STABILE
Department of Pediatrics Catholic University Rome, Italy

Am J Dis Child. 1990;144(6):622.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Sir.—Intravenous gammaglobulin (IVIG) therapy has been used with success in cases of neonatal thrombocytopenia caused by transplacentally transferred maternal autoantibodies^1,2 and in neonatal isoimmune thrombocytopenia.³

Recently we reported a persistent increase in platelet count after 0.4 g/kg per day of intact polyethylene glycol–treated IVIG during the first 5 days of life in a neonate with immune thrombocytopenia, passively acquired from his mother.⁴

In another case, IVIG treatment was without benefit in a neonate with passive immune thrombocytopenia. In this case, the infant's mother had mild thrombocytopenia during the pregnancy (platelet count, 70 x 10⁹/L). Her first child was noted to have thrombocytopenia at 2 months that spontaneously resolved after 2 months.

A male infant was born at term (gestational age, 39 weeks) by vaginal delivery to a woman with a normal pregnancy. His birth weight was 3740 g; Apgar scores were 9 at . . . [Full Text PDF of this Article]

Footnotes
Reprint requests to Cl. Pediatrica, Universita Cattolica, L.go F. Vito, 1, 00168 Roma, Italy (Ms Pesaresi).

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