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J. B. GOUYON, MD; L. PRADEAUX, MD
Service de Pédiatrie 2

VINCENT BOGGIO, MD
Service d'Explorations Fonctionnelles Hôpital d'Enfants 10 Bd Maréchal de Lattre de Tassigny 21034 Dijon Cedex France

Am J Dis Child. 1990;144(11):1181.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Sir.—The article by Sindel et al¹ provides interesting new data suggesting that asymptomatic infants present with frequent gastroesophageal reflux (GER) in the proximal esophagus, and mechanical ventilation might be associated with a decline in gastroesophageal reflux in infants with bronchopulmonary dysplasia. Our own data about distal esophageal pH recordings strengthen these observations.

We investigated 42 mechanically ventilated premature infants (27 to 36 weeks' gestation), maintained in a supine position and parenterally fed. The duration of recordings ranged from 37 to 120 hours (mean [—SD], 94±28 hours). The mean (±SD) values for the percentage of time with distal esophageal pH less than 4, the number of acid GER episodes per hour, and the number of GER episodes lasting for more than 5 minutes per hour were 3.5% ± 3.3%; 1.2 ±1.4 episodes; and 0.08 ±0.09 episodes, respectively. These results did not exceed values we previously obtained in 46 asymptomatic neonates . . . [Full Text PDF of this Article]

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