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  Vol. 142 No. 1, January 1988 TABLE OF CONTENTS
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Breast Milk Opioids and Neonatal Apnea

ERIC G. NAUMBURG, MD; ROBERT G. MENY, MD
Sudden Infant Death Syndrome Institute Department of Pediatrics University of Maryland Hospital 22 S Greene St Baltimore, MD 21201

Am J Dis Child. 1988;142(1):11-12.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Sir.—Based on their timing and apparently benign outcome, Duffty and Bryan1 have suggested that the cause of episodes of apnea occurring in full-term infants in the first week of life is related to events in the perinatal period. We reviewed one year's experience (July 1, 1984, to June 30, 1985) with full-term infants referred for episodes of apnea, bradycardia, and/or cyanosis that occurred in the first week of life, concentrating on perinatal factors. Data presented herein suggest that infant exposure to prescribed opioids in breast milk might be a causative factor.

Patients and Methods.—Selection criteria were as follows: (1) the infant was born at full term (≥37 weeks); (2) the first episode of apnea (>20 s), bradycardia (rate <80 beats per minute for ≥5 s), or cyanosis occurred in the hospital between 0.5 and 7.0 days of age; and (3) the episodes were unexplained, ie, not related . . . [Full Text PDF of this Article]



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