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  Vol. 141 No. 9, September 1987 TABLE OF CONTENTS
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Effects of Intrauterine Exposure to Alkaloidal Cocaine ('Crack')

Patrick E. LeBlanc, MD; Aruna J. Parekh, MD; Barbara Naso; Leonard Glass, MD
Department of Pediatrics State University of New York Health Science Center Box 49 450 Clarkson Ave Brooklyn, NY 11203

Am J Dis Child. 1987;141(9):937-938.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Sir.—The dramatic increase in the use of alkaloidal cocaine ("crack") during Pregnancy has led to a growing concern about its effect on exposed [ill]etuses.1-3 Since crack vaporizes at relatively low temperatures, it can be smoked, with a large quantity of the drug absorbed by the pulmonary vasculature. This leads to a rapid onset of [ill]uphoria, which disappears in about 30 minutes. The repeated use of crack to [ill]egain the euphoric state leads to a [ill]igh level of fetal exposure. Cocaine [ill]as a profound effect on catecholamine metabolism and cardiovascular func[ill]ion,4 and the exposed fetus may be [ill]laced in jeopardy for both short- and [ill]ong-term adverse effects.

Patients and Methods.—This report rep[ill]esents a preliminary study in which we describe the clinical findings observed in 38 infants (21 male, 17 female) of crack-abus[ill]ng mothers who were admitted to our [ill]pecial-care nursery over a four-month pe[ill]iod. All the mothers denied . . . [Full Text PDF of this Article]



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