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Bruce Buckingham, MD; Ann Kershnar, MD
Department of Pediatric Endocrinology

Nick Anas, MD
Department of Critical Care Medicine

Christy Sandborg, MD
Department of Pediatric Rheumatology Childrens Hospital of Orange County PO Box 5700 Orange, CA 92268

Jouni Uitto, MD, PhD
Division of Dermatology UCLA School of Medicine

Am J Dis Child. 1987;141(3):245.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In Reply.—We appreciate the additional information offered by Dr Madácsy. His findings¹ were consistent with those of our studies.² As he suggested, we did analyze our data to compare the vital capacities between diabetic patients with LJM and those without LJM, but we found no significant difference between the two groups by X², multiway table, or linear regression analysis. In a previous study of three diabetic patients with severe LJM, we performed detailed pulmonary function tests, including spirometry, body plethysmography, nitrogen washout curves, and arterial blood gas measurements.³ In these patients, we demonstrated decreased vital capacities, decreased total lung capacities, an abnormal slope of phase III of the nitrogen washout curve, and abnormal oxygenation; however, the patients had normal airway resistance and normal PEF₅₀ and, therefore, had no evidence of obstructive airway disease. To examine a large number of children (N = 375) at a . . . [Full Text PDF of this Article]

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