• Online Features  This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (2)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Ahmad A. Mallouh, MD
PO Box 76 c/o Aramco 31311 Dhahran Saudi Arabia

Am J Dis Child. 1987;141(12):1251.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Sir.—Infarction of the long bones in patients with sickle cell disease is associated with swelling, warmth, redness, pain, and tenderness over a part or the entire shaft of the affected bone.¹ Bone destruction and periosteal reaction with new bone formation are usually evident approximately two weeks after the onset of symptoms.^1,2 This clinical and radiologic picture is indistinguishable from that of osteomyelitis, and it is different from the "typical" painful vaso-occlusive crises that are probably caused by infarction of bone marrow.^1-5 Periosteal elevation and new bone formation is believed to due to an inflammatory reaction, edema, and exudate.^2,6

Report of Cases.—Needle aspiration was performed in 12 Saudi children with homozygous sickle cell disease who presented with fever and swelling, warmth, and tenderness of the long bones (five tibiae, three femora, and four humeri); 2 to 5 mL of bloody or serosanguineous fluid was obtained . . . [Full Text PDF of this Article]

CiteULike    Connotea    Delicious    Digg    Facebook    Reddit    Technorati    Twitter     What's this?