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FRANK E. BERKOWITZ, MB, BCH, FCP(SA); PREETI VALLABH, MB, BCH, FCP(SA); DENNIS I. ALTMAN, MB, BCH, FCP(SA); FRIDERIKI DIAMANTES, MD; HENDRIK J. P. VAN WYK, MSC; JOHANNA M. M. STROUCKEN, NDMT(SA)

Am J Dis Child. 1983;137(6):599.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The Jarisch-Herxheimer reaction, characterized by high fever and chills followed by hypotension and sweating, is a recognized complication of treatment of spirochetal infections, such as borreliosis and syphilis, and of bacterial infections, such as brucellosis and tularemia.¹ We report a case of this reaction developing during treatment of meningococcal meningitis.

Endotoxin Assay.—Plasma endotoxin levels were determined by the Limulus amebocyte lysate test.² Briefly, plasma was incubated with lysate, the protein precipitate was measured by relative light scatter, and this was compared graphically with that produced by endotoxin of Escherichia coli 055:B5.

Report of a Case.—A 9-year-old girl was admitted to Baragwanath Hospital, Johannesburg, Republic of South Africa, on Sept 23, 1981, with a history of fever and confusion beginning on the previous day. Examination showed that she had a temperature of 38.2 °C, a pulse rate of 110 beats per minute, and a BP of 120/70 . . . [Full Text PDF of this Article]

Author Affiliations
Baragwanath Hospital and University of Witwatersrand; Sabax Laboratories Johannesburg, Republic of South Africa

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