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ADRIANO LAZZARIN, MD
Istituto di Malattie Infettive University of Milan Via G. B. Grassi, 74 20157 Milan, Italy

FRANCO CAPSONI, MD
Istituto di Clinica Medica II

ANNA M. TORTORANO, MB
Istituto di Igiene University of Milan Via F. Sforza, 35 20122 Milan, Italy

Am J Dis Child. 1982;136(7):654.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Sir.—It is well known that disseminated aspergillosis in immunocompromised patients is a fatal disease. In children affected by chronic granulomatous disease (CGD), therapy with amphotericin B alone is only marginally effective, and granulocyte transfusions or a surgical approach are often required.

Corrado et al¹ suggested the combined use of rifampin and amphotericin B to treat a child with CGD and aspergillosis.

We report a new case of systemic infection caused by Aspergillus fumigatus in a boy suffering from CGD in whom successful treatment has been obtained with the combination of amphotericin B and rifampin.

Report of a Case.—A 14-year-old boy who had CGD² was admitted to the Division of Infectious Diseases, University of Milan, Italy, because he was febrile (39.5 °C) and had right-sided pneumonia with pleural effusion and two fluctuant masses over the lateral aspect of the chest wall on the right side. The diagnosis . . . [Full Text PDF of this Article]

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