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Multiple Hepatic Hemangiomas: Failure of Corticosteroid Therapy and Successful Hepatic Artery Ligation
KEVIN SHANNON, MD;
GEORGE R. BUCHANAN, MD;
THEODORE P. VOTTELER, MD
Am J Dis Child. 1982;136(3):275-276.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Multinodular hemangiomatosis of the liver generally occurs in the first six months of life, with the triad of hepatomegaly, high-output congestive heart failure, and cutaneous hemangiomas.1 Early reviews described a poor prognosis with death, generally due to intractable congestive heart failure, occurring within the first year.1,2 More recent reports suggest that a favorable outcome usually results from vigorous supportive care and high-dose corticosteroid therapy.2-4 We have recently encountered two patients, however, who received long-term high-dose corticosteroid therapy without apparent response. In one instance, spontaneous involution and hemodynamic improvement was noted; in the other, hepatic artery ligation was performed successfully. Both patients are alive and well more than two years after diagnosis.
Report of Cases.—CASE 1.—This infant was well until 3 months of age when poor feeding, respiratory distress, and two episodes of dusky skin color with feedings were noted. Physical examination disclosed an acutely ill
. . . [Full Text PDF of this Article]
Author Affiliations
University of Texas Health Science Center Southwestern Medical School and Children's Medical Center Dallas
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